Difficult diagnosis, overlap with other conditions, lack of objective signs, the absence of proven treatment. . . these reviews of chronic fatigue syndrome filter and summarize the most rigorous evidence available.
The "Green Berets" of the brain, microglia cells, become hyperactive in fibromyalgia and are key to causing symptoms, said a psychologist and neuroscientist. Finding ways to control them is the key to future treatments, he feels.
The DAS28 disease-activity score has made the transition from research to clinic, but in some circumstances it may be misleading. A tool developed by a rheumatologist can help you explore how changes in components like ESR affect the score in unexpected ways.