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Juvenile Arthritis

Juvenile Arthritis

In a 30-year-old woman with decreased range of motion in several joints, radiographs show bony fusion, profound osteopenia, erosions and advanced arthrosis.

A study from Holland finds that doctors consider patient factors first and cost factors second when choosing treatments for juvenile idiopathic arthritis.

New from the nonspecialty journals: Booster shots OK in juvenile arthritis; suggestions for screening after fungus-contaminated methylprednisolone injections; another manifestation of IgG4-related disease, and more.

EULAR 2013: Interim results from the CHERISH trial of resistent juvenile idiopathic arthritis show lasting efficacy for monthly doses of 8 or 10 mg/kg of tocilizumab.

The FDA has approved canakinumab (Ilaris) for treatment of active systemic juvenile idiopathic arthritis) in patients aged 2 years and older. The drug is administered monthly by subcutaneous injection.

Two major examples of "crowdsourcing" genetic explanations for rheumatic diseases: a competition to explain the genetics of anti-TNF response in rheumatoid arthritis, and 14 newfound genes for juvenile idiopathic arthritis.

An analysis of adverse events in 17 global clinical trials of adalimumab (Humira) confirms the drug’s safety profile over nearly a dozen years of use for rheumatoid arthritis and other inflammatory disorders. Serious infections were the most common side effect.


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