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Spondyloarthritis

Spondyloarthritis

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An increased risk of cardiovascular disease is present in early rheumatoid arthritis and early spondyloarthritis, new research shows.

Improvements were seen in some patients participating in a phase 3 clinical trial as quickly as 4 weeks after the first treatment.

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Patients with psoriatic arthritis achieve significant improvements in signs and symptoms with the interleukin-12/23 inhibitor ustekinumab (Stelara), and they maintain those gains for 2 years, according to final results from 3 major clinical trials.

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A rheumatologist picks 5 studies he found particularly noteworthy at EULAR and gets right to the point about their potential clinical implications.

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The first study to assess the effects of DMARDs or anti-TNF treatment in a real world population of patients with inflammatory arthritis shows a clinically significant improvement in work disability, productivity loss, and disease activity-- especially in those receiving TNF-α blockers.

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Many patients with ankylosing spondylitis have aortic regurgitation: this study makes the case for routine echocardiography evaluation.

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Only 1% to 3% of patients with non-radiographic axial spondyloarthritis achieve remission or low disease activity without TNF-α blockers, but these agents are not yet approved for this use in the US.

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